Metallaaromatic Biaryl Atropisomers
Metallaaromatic Biaryl Atropisomers
Synthesis of stable irida-binaphthyl and -phenanthryl complexes, the first examples of metallaaromatic biaryl atropisomers, has been achieved. The combination of experimental and theoretical studies revealed that the nature of these systems is comparable to that of well-known 1,1`-binaphthalene both in terms of aromaticity and atropisomerism.
Metallaaromatic biaryl atropisomers were obtained and theoretically studied for the first time. Furthermore, relative configuration assignment of atropisomeric diastereoisomers was possible by {1H,1H} NOESY NMR and theoretical analysis. On the other hand, the synthesis, isolation, and characterization of stable iridaphenanthrene complexes presented herein has no precedent and provides evidence for the versatility of our synthetic methodology of giving access to larger polycyclic metallaaromatic systems. The aromatic character along with the stability and atropisomeric nature of these compounds represent the birth of metallaaromatic biaryl atropisomers. New analogs with larger rotational barriers to fully explore the potential of this new family of aromatic compounds are in progress.
Synthesis of stable irida-binaphthyl and -phenanthryl complexes, the first examples of metallaaromatic biaryl atropisomers, has been achieved. The combination of experimental and theoretical studies revealed that the nature of these systems is comparable to that of well-known 1,1`-binaphthalene both in terms of aromaticity and atropisomerism.
Metallaaromatic biaryl atropisomers were obtained and theoretically studied for the first time. Furthermore, relative configuration assignment of atropisomeric diastereoisomers was possible by {1H,1H} NOESY NMR and theoretical analysis. On the other hand, the synthesis, isolation, and characterization of stable iridaphenanthrene complexes presented herein has no precedent and provides evidence for the versatility of our synthetic methodology of giving access to larger polycyclic metallaaromatic systems. The aromatic character along with the stability and atropisomeric nature of these compounds represent the birth of metallaaromatic biaryl atropisomers. New analogs with larger rotational barriers to fully explore the potential of this new family of aromatic compounds are in progress.
